The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Dec. 07, 2012
Applicants:

Rong Chen, Jiangsu, CN;

Lin Feng, Jiangsu, CN;

Zhengping Zhang, Jiangsu, CN;

Fang Fang, Jiangsu, CN;

Qingli Dong, Jiangsu, CN;

Fulong LI, Jiangsu, CN;

Lei Wang, Jiangsu, CN;

Yao Hua, Jiangsu, CN;

Shibao Yang, Jiangsu, CN;

Peng Wang, Jiangsu, CN;

Inventors:

Rong Chen, Jiangsu, CN;

Lin Feng, Jiangsu, CN;

Zhengping Zhang, Jiangsu, CN;

Fang Fang, Jiangsu, CN;

Qingli Dong, Jiangsu, CN;

Fulong Li, Jiangsu, CN;

Lei Wang, Jiangsu, CN;

Yao Hua, Jiangsu, CN;

Shibao Yang, Jiangsu, CN;

Peng Wang, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/14 (2006.01); C07D 471/14 (2006.01); C07D 471/04 (2006.01); C07D 471/12 (2006.01); C07D 491/14 (2006.01);
U.S. Cl.
CPC ...
C07D 495/14 (2013.01); C07D 471/04 (2013.01); C07D 471/12 (2013.01); C07D 471/14 (2013.01); C07D 491/14 (2013.01);
Abstract

Disclosed are 1,4-dihydro-naphthyridine derivatives and pharmaceutical composition and uses thereof. The 1,4-dihydro-naphthyridine derivatives are a compound capable of inhibiting acetylcholinesterase activity and preventing extracellular calcium from flowing into a cell via a calcium channel, i.e., having a dual-activity, which are of potential importance as a pharmaceutical and can be used to prepare the drugs for treating cardiovascular diseases, cerebrovascular diseases and dementia.


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