The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Oct. 10, 2014
Applicant:

Advinus Therapeutics Private Limited, Bangalore, IN;

Inventors:

Venkata Palle, Hinjewadi Pune, IN;

Vidya Ramdas, Hinjewadi Pune, IN;

Dinesh Barawkar, Hinjewadi Pune, IN;

Sujay Basu, Hinjewadi Pune, IN;

Summon Koul, Hinjewadi Pune, IN;

Yogesh Waman, Hinjewadi Pune, IN;

Meena Patel, Hinjewadi Pune, IN;

Anil Panmand, Hinjewadi Pune, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/522 (2006.01); C07D 473/28 (2006.01); C07D 473/40 (2006.01); C07D 473/06 (2006.01); C07D 473/18 (2006.01); C07D 473/30 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 473/40 (2013.01); A61K 31/522 (2013.01); A61K 31/5377 (2013.01); C07D 473/06 (2013.01); C07D 473/18 (2013.01); C07D 473/30 (2013.01);
Abstract

The present invention discloses substituted fused pyrimidine compounds of formula (I), their tautomers, polymorphs, stereoisomers, solvates, pharmaceutically acceptable salts, or pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by adenosine receptor (AR) activity; the compounds of the present invention are useful in the treatment, prevention or suppression of diseases and disorders that may be susceptible to improvement by antagonism of the adenosine receptor, such as asthma, chronic obstructive pulmonary disorder, angiogenesis, pulmonary fibrosis, emphysema, allergic diseases, inflammation, reperfusion injury, myocardial ischemia, atherosclerosis, hypertension, congestive heart failure, retinopathy, diabetes mellitus, obesity, inflammatory gastrointestinal tract disorders, and/or autoimmune diseases.


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