The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Jun. 10, 2013
Gerben Albert Eleutherius Van 't Klooster, Mechelen, BE;
Florence Sylvie Namour, Romainville, FR;
Réginald Christophe Xavier Brys, Mechelen, BE;
Luc Juliaan Corina Van Rompaey, Mechelen, BE;
Gerben Albert Eleutherius van 't Klooster, Mechelen, BE;
Florence Sylvie Namour, Romainville, FR;
Réginald Christophe Xavier Brys, Mechelen, BE;
Luc Juliaan Corina van Rompaey, Mechelen, BE;
GALAPAGOS NV, Mechelen, BE;
Abstract
The present invention relates to the compound according to Formula I, and to its use in medicine, in particular in the treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons. In particular, the compound inhibits JAK a family of tyrosine kinases, and more particularly JAK1. The present invention also provides pharmaceutical compositions comprising the compound, methods for the prophylaxis and/or treatment of diseases involving inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons by administering the compound.