The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Oct. 11, 2012
Applicants:

Konstanze Hurth, Lorrach, DE;

Sebastien Jacquier, Hegenheim, FR;

Rainer Machauer, Freiburg, DE;

Heinrich Rueeger, Flueh, CH;

Marina Tintelnot-blomley, Maulburg, DE;

Siem Jacob Veenstra, Lorrach, DE;

Markus Voegtle, Lorrach, DE;

Inventors:

Konstanze Hurth, Lorrach, DE;

Sebastien Jacquier, Hegenheim, FR;

Rainer Machauer, Freiburg, DE;

Heinrich Rueeger, Flueh, CH;

Marina Tintelnot-Blomley, Maulburg, DE;

Siem Jacob Veenstra, Lorrach, DE;

Markus Voegtle, Lorrach, DE;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 265/30 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 31/5375 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 265/30 (2013.01); A61K 31/5375 (2013.01); A61K 31/5377 (2013.01); C07D 413/04 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.


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