The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Dec. 13, 2011
Applicants:

Gerard Griffioen, Linden, BE;

Tom Van Dooren, Lier, BE;

Verónica Rojas DE LA Parra, Haasrode, BE;

Arnaud Marchand, Korbeek/Lo, BE;

Sara Alassia, Mechelen, BE;

Amuri Kilonda, Roosbeek-Boutersem, BE;

Patrick Chaltin, Jodoigne, BE;

Inventors:

Gerard Griffioen, Linden, BE;

Tom Van Dooren, Lier, BE;

Verónica Rojas De La Parra, Haasrode, BE;

Arnaud Marchand, Korbeek/Lo, BE;

Sara Alassia, Mechelen, BE;

Amuri Kilonda, Roosbeek-Boutersem, BE;

Patrick Chaltin, Jodoigne, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/14 (2006.01); C07D 209/18 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 209/18 (2013.01); C07D 209/14 (2013.01); C07D 401/12 (2013.01); C07D 409/12 (2013.01); C07D 471/04 (2013.01);
Abstract

This invention provides novel compounds and the novel compounds for use as a medicine, more in particular for the prevention or treatment of neurodegenerative disorders, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, and disorders characterized by cytotoxic α-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such neurodegenerative disorders. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds. The compounds have the formula (A1), wherein R, R, R, R, R, E, n, Y, Y, Y, Y, Y, B, R, and m are as defined in the claims.


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