The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
May. 10, 2012
Applicants:
Ronit Satchi-fainaro, Tel-Aviv, IL;
Gianfranco Pasut, Padua, IT;
Inventors:
Ronit Satchi-Fainaro, Tel-Aviv, IL;
Gianfranco Pasut, Padua, IT;
Assignees:
Ramot at Tel-Aviv University Ltd., Tel-Aviv, IL;
Universita degli Studi di Padova, Padua, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 47/24 (2006.01); A61K 49/00 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/24 (2013.01); A61K 47/48084 (2013.01); A61K 47/48215 (2013.01); A61K 49/0008 (2013.01); G01N 33/5091 (2013.01); G01N 33/574 (2013.01); A61K 47/48169 (2013.01); A61K 47/48253 (2013.01);
Abstract
Polymeric conjugates comprising a polymeric backbone having attached thereto a bone targeting moiety and a therapeutically active agent, wherein the bone targeting moiety is attached to one end of the polymeric backbone via a branching unit such that a molar ratio of the bone targeting moiety to the polymer is at least 2:1, are disclosed. Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed.