The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Feb. 21, 2012
Emmanuel Opara, Durham, NC (US);
James J. Yoo, Winston-Salem, NC (US);
Justin M. Saul, Winston-Salem, NC (US);
Sittadjody Sivanandane, Winston-Salem, NC (US);
Anthony Atala, Winston-Salem, NC (US);
Emmanuel Opara, Durham, NC (US);
James J. Yoo, Winston-Salem, NC (US);
Justin M. Saul, Winston-Salem, NC (US);
Sittadjody Sivanandane, Winston-Salem, NC (US);
Anthony Atala, Winston-Salem, NC (US);
Wake Forest University Health Sciences, Winston-Salem, NC (US);
Abstract
A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described.