The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Mar. 29, 2011
Applicants:
Devanand Sarkar, Richmond, VA (US);
Paul B. Fisher, Richmond, VA (US);
Inventors:
Devanand Sarkar, Richmond, VA (US);
Paul B. Fisher, Richmond, VA (US);
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/7105 (2006.01); C07K 16/18 (2006.01); C07K 16/30 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); C12N 5/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); C07K 16/18 (2013.01); C07K 16/303 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57438 (2013.01); A61K 2039/505 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Inhibitors of Late SV-40 Factor (LSF) are used to treat cancers such as hepatocellular carcinoma (HCC). In particular, small molecule chemical LSF inhibitors are employed. In addition, the activity and/or pattern of expression of LSF may is used to diagnose cancer, to characterize the cancer (e.g. stage, grade, prognosis, etc.) and also to develop suitable protocols for cancer treatment.