The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Jun. 01, 2011
Applicants:
Sunghee Cho, Hastings on Hudson, NY (US);
Yi Bao, Chestnut Hill, MA (US);
Eunhee Kim, White Plains, NY (US);
Inventors:
Sunghee Cho, Hastings on Hudson, NY (US);
Yi Bao, Chestnut Hill, MA (US);
Eunhee Kim, White Plains, NY (US);
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7088 (2006.01); A61K 31/343 (2006.01); A61K 31/19 (2006.01); A61K 31/4375 (2006.01); C07K 16/28 (2006.01); C12Q 1/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 31/19 (2013.01); A61K 31/343 (2013.01); A61K 31/4375 (2013.01); C07K 16/2896 (2013.01); A61K 2039/505 (2013.01);
Abstract
The disclosure relates to the therapeutic utility of CD36 antagonists to reduce body weight, inhibit fat accumulation and especially visceral fat accumulation, improve insulin sensitivity, lower blood glucose levels, and treat and prevent metabolic syndrome, pre-diabetes and diabetes, and lower plasma cholesterol levels and decrease fat deposit in the liver. CD36 antagonists, including SAB or its metabolites, such as RA and DSS, are useful for these purposes.