The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Aug. 15, 2011
Applicants:

Scott Clunas, Old Aberdeen, GB;

John Mervyn David Storey, Old Aberdeen, GB;

James Peter Sinclair, Old Aberdeen, GB;

Thomas Craven Baddeley, Old Aberdeen, GB;

Ahtsham Ishaq, Old Aberdeen, GB;

Michael Simpson, Old Aberdeen, GB;

Craig Williamson, Surrey, GB;

Barry Alan Wood, Old Aberdeen, GB;

Claude Michel Wischik, Old Aberdeen, GB;

Charles Robert Harrington, Old Aberdeen, GB;

Janet Elizabeth Rickard, Old Aberdeen, GB;

David Horsley, Old Aberdeen, GB;

Yin Sze Loh, Singapore, SG;

Colin Marshall, Old Aberdeen, GB;

Karrar Ahmad Khan, Old Aberdeen, GB;

Inventors:

Scott Clunas, Old Aberdeen, GB;

John Mervyn David Storey, Old Aberdeen, GB;

James Peter Sinclair, Old Aberdeen, GB;

Thomas Craven Baddeley, Old Aberdeen, GB;

Ahtsham Ishaq, Old Aberdeen, GB;

Michael Simpson, Old Aberdeen, GB;

Craig Williamson, Surrey, GB;

Barry Alan Wood, Old Aberdeen, GB;

Claude Michel Wischik, Old Aberdeen, GB;

Charles Robert Harrington, Old Aberdeen, GB;

Janet Elizabeth Rickard, Old Aberdeen, GB;

David Horsley, Old Aberdeen, GB;

Yin Sze Loh, Singapore, SG;

Colin Marshall, Old Aberdeen, GB;

Karrar Ahmad Khan, Old Aberdeen, GB;

Assignee:

WisTa Laboratories Ltd., Singapore, SG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5415 (2006.01); C07D 279/20 (2006.01); C07D 309/04 (2006.01); C07C 309/05 (2006.01); A61K 9/20 (2006.01); C07C 309/04 (2006.01); A61K 9/28 (2006.01); C07C 309/30 (2006.01); C07C 309/35 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5415 (2013.01); A61K 9/2095 (2013.01); C07C 309/04 (2013.01); C07C 309/05 (2013.01); C07D 279/20 (2013.01); A61K 9/2893 (2013.01); C07C 309/30 (2013.01); C07C 309/35 (2013.01);
Abstract

The invention relates to compounds of general formula (I): wherein: each of Rand Ris independently selected from: —H, Calkyl, Calkenyl, and halogenated Calkyl; each of Rand Ris independently selected from: —H, Calkyl, Calkenyl, and halogenated Calkyl; each of R7NA and R7NB is independently selected from: —H, Calkyl, Calkenyl, and halogenated Calkyl; and wherein: each of Rand Ris independently selected from: Calkyl, halogenated Calkyl, and Caryl; or Rand Rare linked to form a group selected from: Calkylene and Carylene; and pharmaceutically acceptable salts thereof, which are useful in the treatment of, for example, Alzheimer's disease. In other aspects the invention also relates to novel formulations of 3,7-diamino-10H-phenothiazinium salts.


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