The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Apr. 05, 2012
Applicants:

Maria Gabriella Brasca, Nerviano, IT;

Tiziano Bandiera, Gambolo, IT;

Jay Aaron Bertrand, Didcot, GB;

Paola Gnocchi, Stresa, IT;

Danilo Mirizzi, Nerviano, IT;

Marcella Nesi, Saronno, IT;

Achille Panzeri, Merate, IT;

Inventors:

Maria Gabriella Brasca, Nerviano, IT;

Tiziano Bandiera, Gambolo, IT;

Jay Aaron Bertrand, Didcot, GB;

Paola Gnocchi, Stresa, IT;

Danilo Mirizzi, Nerviano, IT;

Marcella Nesi, Saronno, IT;

Achille Panzeri, Merate, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07F 5/025 (2013.01);
Abstract

The present invention relates to substituted pyrimidinyl-pyrrole compounds of formula (I) which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Janus kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.


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