The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Jan. 15, 2015
Applicant:

N30 Pharmaceuticals, Inc., Boulder, CO (US);

Inventors:

Xicheng Sun, Broomfield, CO (US);

Jian Qiu, Longmont, CO (US);

Assignee:

Nivalis Therapeutics, Inc., Boulder, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); C07D 419/00 (2006.01); C07D 213/22 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 417/00 (2006.01); C07D 405/00 (2006.01); C07D 403/00 (2006.01); C07D 409/00 (2006.01); C07D 411/00 (2006.01); C07D 413/00 (2006.01); A61K 31/4412 (2006.01); C07D 211/88 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 409/14 (2006.01); C07D 211/86 (2006.01); C07D 409/04 (2006.01); A61K 31/4436 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4412 (2013.01); A61K 31/444 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); C07D 211/86 (2013.01); C07D 211/88 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01);
Abstract

The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.


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