The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2016
Filed:
Jun. 13, 2012
Applicants:
Giulio Cabrini, Verona, IT;
Valeria Casavola, Bari, IT;
Roberto Gambari, Ferrara, IT;
Inventors:
Assignees:
Azienda Ospedaliera Universitaria Integrata di Verona, Verona, IT;
Universita' degli Studi di Ferrara, Ferrara, IT;
Universita' degli Studi di Bari, Bari, IT;
Rare Partners S.r.l., Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/366 (2006.01); A61K 31/37 (2006.01); A61K 31/443 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
A61K 31/366 (2013.01); A61K 31/37 (2013.01); A61K 31/443 (2013.01); A61K 31/47 (2013.01);
Abstract
The invention relates to the use of 4,6,4'-trimethylangelicin (TMA) and structural analogs thereof to prepare a medicament for the treatment of cystic fibrosis with the primary objective of correcting the defective CFTR in a sub-group of cystic fibrosis patients consisting of patients carrying the F508del-CFTR mutation.