The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 2016

Filed:

Jun. 09, 2010
Applicants:

Shalva Mardi, Binningen, CH;

Rosa Mardi, Binningen, CH;

Gymsher Mardi, Binningen, CH;

Laura Mardi, Binningen, CH;

Shimon Slavin, Tel-Aviv, IL;

Inventors:

Shalva Mardi, Binningen, CH;

Rosa Mardi, Binningen, CH;

Gymsher Mardi, Binningen, CH;

Laura Mardi, Binningen, CH;

Shimon Slavin, Tel-Aviv, IL;

Assignee:

Cimas Limited, Nicosia, CY;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/19 (2006.01); A61K 31/194 (2006.01); A61K 31/22 (2006.01); C07C 59/315 (2006.01); C07C 69/63 (2006.01); C07C 69/708 (2006.01);
U.S. Cl.
CPC ...
A61K 31/19 (2013.01); A61K 31/194 (2013.01); A61K 31/22 (2013.01); C07C 59/315 (2013.01); C07C 69/63 (2013.01); C07C 69/708 (2013.01);
Abstract

Halogenated aliphatic carboxylic acids, salts and/or oligomers or polymers thereof, which exhibit a devitalizing effect of neoplastic tissues, are disclosed. Methods and uses that utilize these compounds for the treatment of medical conditions associated with a neoplastic tissue are also disclosed. Further disclosed are methods and uses that utilize these compounds for reducing or abolishing blood and lymph as well local dissemination of malignant neoplastic cells during a surgical removal thereof, thereby preventing recurrences and distance metastases, and/or inducing immune response to potentially malignant, pre-malignant and/or malignant cells. Further disclosed are novel oligomeric forms of halogenated aliphatic carboxylic acids, pharmaceutical compositions containing same and uses thereof.


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