The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2016

Filed:

Aug. 17, 2012
Applicants:

Hye Soon Won, Daejeon, KR;

Byung Je Sung, Daejeon, KR;

Yong Ho Ahn, Daejeon, KR;

Sang Kyung Park, Daejeon, KR;

Inventors:

Hye Soon Won, Daejeon, KR;

Byung Je Sung, Daejeon, KR;

Yong Ho Ahn, Daejeon, KR;

Sang Kyung Park, Daejeon, KR;

Assignee:

ARES TRADING S.A., Aubonne, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); C07K 14/7151 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to a method for separating and preparing a TNFR-Fc fusion protein using hydrophobic interaction chromatography (HIC). More particularly, the present invention relates to a method for separating and preparing a highly pure active protein from clipped proteins due to displacement effect by adjusting the conductivity of a protein sample using a high concentration of salt solution and by adjusting a loading amount thereof, and a TNFR-Fc fusion protein prepared by the method.


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