The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2016

Filed:

Oct. 08, 2009
Applicants:

Kenneth W. Walker, Newbury Park, CA (US);

Colin V. Gegg, Jr., Newbury Park, CA (US);

Randy I. Hecht, Thousand Oaks, CA (US);

Edward J. Belouski, Camarillo, CA (US);

Yue-sheng LI, Thousand Oaks, CA (US);

Mark L. Michaels, Encino, CA (US);

Jing Xu, Thousand Oaks, CA (US);

Murielle M. Ellison, Thousand Oaks, CA (US);

Inventors:

Kenneth W. Walker, Newbury Park, CA (US);

Colin V. Gegg, Jr., Newbury Park, CA (US);

Randy I. Hecht, Thousand Oaks, CA (US);

Edward J. Belouski, Camarillo, CA (US);

Yue-Sheng Li, Thousand Oaks, CA (US);

Mark L. Michaels, Encino, CA (US);

Jing Xu, Thousand Oaks, CA (US);

Murielle M. Ellison, Thousand Oaks, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/50 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/50 (2013.01); A61K 38/00 (2013.01);
Abstract

The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides comprising extended in vivos half-lives, pharmaceutical compositions comprising FGF21 mutant polypeptides having extended in vivos half lives, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.


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