The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2016
Filed:
Aug. 20, 2014
Applicants:
Ulrich Reiser, Vienna, AT;
James Madden, Reading, GB;
Inventors:
Ulrich Reiser, Vienna, AT;
James Madden, Reading, GB;
Assignee:
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/048 (2006.01); C07D 213/75 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); C07D 473/00 (2006.01); C07D 487/04 (2006.01); C07D 401/02 (2006.01); C07D 403/02 (2006.01); C07D 403/14 (2006.01); A61K 31/519 (2006.01); A61K 31/444 (2006.01); A61K 31/435 (2006.01);
U.S. Cl.
CPC ...
C07D 491/048 (2013.01); A61K 31/435 (2013.01); A61K 31/444 (2013.01); A61K 31/519 (2013.01); C07D 213/75 (2013.01); C07D 401/02 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/02 (2013.01); C07D 403/14 (2013.01); C07D 471/04 (2013.01); C07D 473/00 (2013.01); C07D 487/04 (2013.01);
Abstract
This invention relates to 6-alkynyl-pyridine of general formula (I) their use as SMAC mimetics, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups Rto Rhave the meanings given in the claims and in the specification.