The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2016

Filed:

Aug. 11, 2011
Applicants:

Rosemarie Riedl, Vienna, AT;

Klaus Thirring, Vienna, AT;

Werner Heilmayer, Zillingtal, AT;

Inventors:

Rosemarie Riedl, Vienna, AT;

Klaus Thirring, Vienna, AT;

Werner Heilmayer, Zillingtal, AT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 323/52 (2006.01); A61K 31/215 (2006.01); A61P 31/00 (2006.01); A61K 31/235 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 323/52 (2013.01); A61K 31/235 (2013.01); A61K 45/06 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/18 (2013.01); C07C 2102/42 (2013.01); C07C 2102/44 (2013.01); C07C 2103/99 (2013.01);
Abstract

Compounds selected from the group of N-unsubstituted or N-alkylated or N-acylated 14-O-[(amino(C)alkyl-hydroxy-cycloalkyl- or bicycloalkylsulfanyl)-acetyl]-mutilins which are 14-O-[(amino(C)alkyl-hydroxy-cyclobutylsulfanyl)-acetyl]-mutilins, 14-O-[(amino(C)alkyl-hydroxy-cyclopentylsulfanyl)-acetyl]-mutilins, 14-O-[(amino(C)alkyl-hydroxy-cycloheptylsulfanyl)-acetyl]-mutilins, 14-O-[(amino(C)alkyl-hydroxy-cyclooctylsulfanyl)-acetyl]-mutilins, or 14-O-[(amino(C)alkyl-hydroxy-bicycloalkylsulfanyl)-acetyl]-mutilins, optionally in the form of a salt and/or a solvate, a pharmaceutical compositions comprising such compounds and their use as pharmaceuticals, e.g. for the treatment of microbial infections and for the treatment of acne, optionally in combination with other pharmaceutically active agents.


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