The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2016
Filed:
May. 17, 2013
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventor:
Travis Remarchuk, South San Francisco, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 229/30 (2006.01); C07C 269/06 (2006.01); C07C 271/22 (2006.01); C07C 67/343 (2006.01); C07C 67/313 (2006.01); C07C 269/04 (2006.01);
U.S. Cl.
CPC ...
C07C 269/06 (2013.01); C07C 67/313 (2013.01); C07C 67/343 (2013.01); C07C 229/30 (2013.01); C07C 269/04 (2013.01); C07C 271/22 (2013.01); C07B 2200/07 (2013.01);
Abstract
The invention provides new processes for making and purifying amino acid compounds, which are useful in the preparation of AKT inhibitors used in the treatment of diseases such as cancer, including the compound (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one.