The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2016
Filed:
Feb. 25, 2014
Applicant:
Chemapotheca, Llc, Delmar, NY (US);
Inventors:
Harold Meckler, Delmar, NY (US);
Brian Thomas Gregg, Altamont, NY (US);
Jie Yang, Rensselaer, NY (US);
Assignee:
Chemapotheca, LLC, Delmar, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 209/68 (2006.01); C07F 9/564 (2006.01); C07C 209/62 (2006.01); C07F 9/24 (2006.01);
U.S. Cl.
CPC ...
C07C 209/62 (2013.01); C07F 9/2458 (2013.01); C07F 9/2475 (2013.01); C07B 2200/07 (2013.01); C07F 9/564 (2013.01);
Abstract
The invention includes processes for the synthesis of amphetamine, dexamphetamine, methamphetamine, derivatives of these, including their salts, and novel precursors and intermediates obtained thereby, by synthesizing aziridine phosphoramidate compounds in specified solvents at specified temperatures, and then converting to a novel aryl or aryl-alkyl phosphoramidate precursors using an organometallic compound such as a copper salt, where the novel aryl or aryl-alkyl phosphoramidate precursor is then easily converted to the target compounds using known reactions.