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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9278163 B1

PDFFull Text
Date of Patent:
Mar. 08, 2016

Filed:

Oct. 03, 2014

Implantable polymeric device for sustained release of dopamine agonist

Applicant:

Titan Pharmaceuticals, Inc., South San Francisco, CA (US);

Inventors:

Rajesh A. Patel, Redwood City, CA (US);

Louis R. Bucalo, Miami, FL (US);

Lauren Costantini, San Francisco, CA (US);

Sofie Kleppner, Palo Alto, CA (US);

Assignee:

Titan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Jake Vu

Int. Cl.
CPC ...
A61L 31/16 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 31/381 (2006.01); A61K 31/4045 (2006.01); A61K 31/428 (2006.01); A61K 31/48 (2006.01); A61K 31/485 (2006.01); A61L 31/04 (2006.01); A61K 31/198 (2006.01); A61L 31/10 (2006.01); A61L 31/12 (2006.01); A61L 31/14 (2006.01);
U.S. Cl.
CPC ...
A61L 31/16 (2013.01); A61K 9/0024 (2013.01); A61K 9/146 (2013.01); A61K 9/1635 (2013.01); A61K 31/198 (2013.01); A61K 31/381 (2013.01); A61K 31/4045 (2013.01); A61K 31/428 (2013.01); A61K 31/48 (2013.01); A61K 31/485 (2013.01); A61L 31/048 (2013.01); A61L 31/10 (2013.01); A61L 31/125 (2013.01); A61L 31/146 (2013.01); A61L 2300/20 (2013.01); A61L 2300/40 (2013.01); A61L 2300/41 (2013.01); A61L 2300/602 (2013.01); A61L 2300/606 (2013.01); A61L 2300/62 (2013.01); A61L 2420/04 (2013.01);
Abstract

The present invention provides compositions, methods, and kits for treatment of Parkinson's disease and other conditions for which treatment with a dopamine agonist is therapeutically beneficial. The invention provides a biocompatible nonerodible polymeric device which releases dopamine agonist continuously with generally linear release kinetics for extended periods of time. Dopamine agonist is released through pores that open to the surface of the polymeric matrix in which it is encapsulated. The device may be administered subcutaneously to an individual in need of continuous treatment with dopamine agonist.

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