The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2016

Filed:

Nov. 25, 2014
Applicants:

Freie Universität Berlin, Berlin, DE;

Charité Universitätsmedizin Berlin, Berlin, DE;

Inventors:

Martin Stockmann, Berlin, DE;

Björn Riecke, Schwielowsee, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/10 (2006.01); A61B 5/00 (2006.01); A61B 5/097 (2006.01); A61K 49/00 (2006.01); A61K 51/04 (2006.01); A61M 16/06 (2006.01); C12Q 1/26 (2006.01); A61B 5/083 (2006.01); G01N 33/497 (2006.01);
U.S. Cl.
CPC ...
A61K 49/10 (2013.01); A61B 5/00 (2013.01); A61B 5/097 (2013.01); A61B 5/413 (2013.01); A61B 5/4244 (2013.01); A61K 49/0004 (2013.01); A61K 51/04 (2013.01); A61M 16/06 (2013.01); C12Q 1/26 (2013.01); A61B 5/0836 (2013.01); G01N 33/497 (2013.01); G01N 2333/90245 (2013.01); Y10S 436/90 (2013.01);
Abstract

An analysis method determines a functional parameter of an organ by measuringCOcontent in exhaled air of an individual to which a substrate has been administered. The reaction of the substrate in the body of the individual enriches the exhaled air withCO. The maximum reaction rate of the substrate in the body is determined via a change of the measuredCOcontent in the exhaled air using zero-order enzyme kinetics. An aqueous methacetin solution having a pH greater than 7.0 is used in the analysis method. A face mask separates the exhaled air from inhaled air. The face mask is configured such that inhaled and exhaled air flows essentially completely through the face mask. Exhalation and inhalation valves in the face mask allow a flow of inhaled and exhaled air through the face mask. A diagnostic method is used to determine the functional parameters of the organ.


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