The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2016
Filed:
Oct. 28, 2013
Applicants:
Sanaria Inc., Rockville, MD (US);
The Rockefeller University, New York, NY (US);
Inventors:
Sumana Chakravarty, Derwood, MD (US);
Stephen L. Hoffman, Gaithersburg, MD (US);
Moriya Tsuji, New York, NY (US);
Assignees:
SANARIA INC., Rockville, MD (US);
THE ROCKEFELLER UNIVERSITY, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/015 (2006.01); A61K 39/39 (2006.01); A61K 9/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); A61K 9/0019 (2013.01); A61K 9/0021 (2013.01); A61K 39/39 (2013.01); A61K 2039/522 (2013.01); A61K 2039/55511 (2013.01);
Abstract
Disclosed herein are pharmaceutical compositions comprisingsporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host rangeand analogues of α-galactosylceramide (α-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.