The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2016
Filed:
Jul. 16, 2010
Hiromi Takenaka, Tokyo, JP;
Jou Akitomi, Tokyo, JP;
Shintarou Katou, Tokyo, JP;
Shotaro Tsuji, Yokohama, JP;
Takashi Ohtsu, Yokohama, JP;
Iwao Waga, Tokyo, JP;
Hiromi Takenaka, Tokyo, JP;
Jou Akitomi, Tokyo, JP;
Shintarou Katou, Tokyo, JP;
Shotaro Tsuji, Yokohama, JP;
Takashi Ohtsu, Yokohama, JP;
Iwao Waga, Tokyo, JP;
NEC Solution Innovators, Ltd., Tokyo, JP;
Kanagawa Prefectural Hospital Organization, Yokohama-shi, Kanagawa, JP;
Abstract
A nucleic acid molecule that can bind to HMGB1 protein and applications thereof are provided. A nucleic acid molecule having a dissociation constant for HMGB1 protein of 5×10or less can be used as the nucleic acid molecule that can bind to HMGB1 protein. The HMGB1 binding nucleic acid molecule can bind to HMGB1 protein that is known to be a cause of diseases such as cancer and inflammation, and it is therefore possible to obtain an effect to prevent and an effect to treat such diseases by allowing the HMGB1 binding nucleic acid molecule to bind to HMGB1 protein in a living body.