The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 08, 2016

Filed:

Feb. 12, 2015
Applicant:

Summit Therapeutics Plc, Abingdon, Oxfordshire, GB;

Inventors:

Peter David Johnson, Abingdon, GB;

Richard John Vickers, Abingdon, GB;

Francis Xavier Wilson, Abingdon, GB;

Colin Richard Dorgan, Abingdon, GB;

Lauren Jayne Sudlow, Abingdon, GB;

Stephen Paul Wren, Abingdon, GB;

Renate Maria van Well, Abingdon, GB;

Assignee:

Summit Therapeutics PLC, Abingdon, Oxfordshire, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 31/4164 (2006.01); A61K 31/444 (2006.01); A61K 31/424 (2006.01); A61K 31/546 (2006.01); A61K 35/741 (2015.01); A61K 38/14 (2006.01); A61K 45/06 (2006.01); C07D 401/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); C07D 401/14 (2006.01); A61K 31/4439 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); A61K 31/4365 (2006.01); A61K 31/437 (2006.01); A61K 31/74 (2006.01); A61K 35/747 (2015.01); A61K 36/064 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 31/444 (2013.01); A61K 31/4164 (2013.01); A61K 31/424 (2013.01); A61K 31/437 (2013.01); A61K 31/4365 (2013.01); A61K 31/4439 (2013.01); A61K 31/546 (2013.01); A61K 31/74 (2013.01); A61K 35/741 (2013.01); A61K 35/747 (2013.01); A61K 36/064 (2013.01); A61K 38/14 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01);
Abstract

Disclosed are compounds of formula (I): and pharmaceutically acceptable N-oxides, salts, hydrates, solvates, complexes, bioisosteres, metabolites, and prodrugs thereof, which are of use in the treatment of infection with, and diseases caused by,


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