The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 2016
Filed:
Apr. 11, 2013
Applicants:
Marcia Macdonald, Vancouver, CA;
Mark Samuels, Westmount, CA;
Robin Sherrington, West Vancouver, CA;
Yigal Paul Goldberg, Vancouver, CA;
Inventors:
Marcia MacDonald, Vancouver, CA;
Mark Samuels, Westmount, CA;
Robin Sherrington, West Vancouver, CA;
Yigal Paul Goldberg, Vancouver, CA;
Assignee:
Xenon Pharmaceuticals Inc., Burnaby, B.C., CA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 31/40 (2006.01); A01N 43/38 (2006.01); C07H 21/04 (2006.01); A61K 31/407 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/407 (2013.01); C12Q 1/6897 (2013.01); A01N 43/38 (2013.01); A61K 31/40 (2013.01); C07H 21/04 (2013.01); C12Q 2600/112 (2013.01);
Abstract
The present invention relates to the discovery that mutations in SCN9A are causative of Congenital Indifference to Pain (CIP) in humans. The invention also relates to methods of using compounds small organic compounds to treat pain as well as to predict the effect of analgesic agents in patients, such as those possessing gain of function mutations.