The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2016

Filed:

Dec. 21, 2012
Applicant:

Optotrace (Suzhou) Technologies, Inc., SuZhou, CN;

Inventors:

Xun Guo, San Jose, CA (US);

Chunwei Liu, Beijing, CN;

Anping Deng, SuZhou, CN;

Huafang Chang, SuZhou, CN;

Hong Wang, Cupertino, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/558 (2006.01); G01N 33/543 (2006.01); B82Y 30/00 (2011.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
G01N 33/54346 (2013.01); B82Y 30/00 (2013.01); B82Y 5/00 (2013.01);
Abstract

An integrated chromatography-immunoassay system for integrated chromatography-immunoassay system includes a chromatographic unit that receives labeled nano-structured probes comprising nano particles and antibodies attached to the nano particles, and a test membrane comprising coating antigens. The chromatographic unit allows the labeled nano-structured probes to diffuse there through and into the test membrane, wherein the antibodies on the nano particles are bound to the coating antigens. A laser device emits a laser light to illuminate the labeled nano-structured probes having the antibodies bound to the coating antigens on the test membrane. A spectral analyzer obtains a Raman spectrum from light scattered from the labeled nano-structured probes having the antibodies bound to the coating antigens on the test membrane, and to identify a spectral signature in the Raman spectrum associated with the antibody-antigen pair, which enables detection and identification of the antibody.


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