The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Feb. 10, 2012
Applicants:
Rudi Fasan, Rochester, NY (US);
Kaidong Zhang, Chilliwack, CA;
Inventors:
Rudi Fasan, Rochester, NY (US);
Kaidong Zhang, Chilliwack, CA;
Assignee:
University of Rochester, Rochester, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/08 (2006.01); C12Q 1/26 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/26 (2013.01); C12N 15/102 (2013.01); C12N 15/1093 (2013.01); C40B 30/08 (2013.01); G01N 2333/90241 (2013.01); G01N 2333/90245 (2013.01);
Abstract
Methods and systems for evaluating and predicting the reactivity of natural and engineered monooxygenase enzymes are provided. Methods are provided for acquiring a functional profile (fingerprint) of monooxygenases that encode information regarding the active site configuration of such monooxygenases. Methods are also provided for carrying out analysis of a monooxygenase fingerprint, to formulate predictions regarding the reactivity properties (e.g., substrate reactivity, chemo-, regio, and stereoselectivity properties) of the fingerprinted monooxygenases.