The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
May. 23, 2011
Thomas Primiano, Monona, WI (US);
Lonnie Bookbinder, Corvallis, MT (US);
Bey-dih Chang, Madison, WI (US);
Jeremy Heidel, Madison, WI (US);
Thomas Primiano, Monona, WI (US);
Lonnie Bookbinder, Corvallis, MT (US);
Bey-Dih Chang, Madison, WI (US);
Jeremy Heidel, Madison, WI (US);
PeptiMed, Inc., Madison, WI (US);
Abstract
This invention describes a genetic system for targeting the EVI1 gene in mammalian cells. The EVI1 gene is an oncogenic transcription factor that, when expressed, accelerates cell division and inhibits death of cells. Nucleotide sequences that block the expression of EVI1 and drug delivery systems for them are described. These nucleotide sequences cause a block in cell growth and division and trigger death of mammalian cells, including lung and ovarian cancer cells.