The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2016

Filed:

Mar. 05, 2010
Applicants:

Gwynedd A. Benders, Portland, OR (US);

John I. Glass, Germantown, MD (US);

Clyde A. Hutchison, Iii, La Jolla, CA (US);

Carole Lartigue, Residence des Arenes Bayonne, FR;

Sanjay Vashee, Boyds, MD (US);

Mikkel A. Algire, Jessup, MD (US);

Hamilton O. Smith, San Diego, CA (US);

Charles E. Merryman, Sykesville, MD (US);

Vladimir N. Noskov, Montgomery Village, MD (US);

Ray-yuan Chuang, Rockville, MD (US);

Daniel G. Gibson, Crofton, MD (US);

J. Craig Venter, La Jolla, CA (US);

Inventors:

Gwynedd A. Benders, Portland, OR (US);

John I. Glass, Germantown, MD (US);

Clyde A. Hutchison, III, La Jolla, CA (US);

Carole Lartigue, Residence des Arenes Bayonne, FR;

Sanjay Vashee, Boyds, MD (US);

Mikkel A. Algire, Jessup, MD (US);

Hamilton O. Smith, San Diego, CA (US);

Charles E. Merryman, Sykesville, MD (US);

Vladimir N. Noskov, Montgomery Village, MD (US);

Ray-Yuan Chuang, Rockville, MD (US);

Daniel G. Gibson, Crofton, MD (US);

J. Craig Venter, La Jolla, CA (US);

Assignee:

Synthetic Genomics, Inc., La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); C12N 15/10 (2013.01); C12N 15/1031 (2013.01); C12N 15/1079 (2013.01);
Abstract

Compositions and methods are disclosed herein for cloning a donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.


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