The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9273300 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 01, 2016

Filed:

Feb. 07, 2008
Applicants:

Phillip Maples, Pilot Point, TX (US);

Chris Jay, Grapevine, TX (US);

John J. Nemunaitis, Cedar Hill, TX (US);

Inventors:

Phillip Maples, Pilot Point, TX (US);

Chris Jay, Grapevine, TX (US);

John J. Nemunaitis, Cedar Hill, TX (US);

Assignee:

STRIKE BIO, INC, Dallas, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01); C12N 9/90 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 9/90 (2013.01); A61K 48/005 (2013.01); C12N 15/85 (2013.01);
Abstract

According to certain embodiments of the present invention, methods for modulating the production of sialic acid in a system are provided, which comprise providing the system with a wild-type GNE-encoding nucleic acid sequence. According to such embodiments, the system may comprise a cell, muscular tissue, or other desirable targets. Similarly, the present invention encompasses methods for producing wild-type GNE in a system that comprises a mutated endogenous GNE-encoding sequence. In other words, the present invention includes providing, for example, a cell or muscular tissue that harbors a mutated (defective) GNE-encoding sequence with a functional wild-type GNE encoding sequence.


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