The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Nov. 23, 2011
Applicants:
Ingo Jordan, Berlin, DE;
Holger Bernhardt, Berlin, DE;
Stefan Hartmann, Berlin, DE;
Inventors:
Assignee:
PROBIOGEN AG, Berlin, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/02 (2006.01);
U.S. Cl.
CPC ...
C12N 7/02 (2013.01); C12N 2710/24151 (2013.01);
Abstract
It is desirable to produce live vaccines, which are highly attenuated and which do only contain minimal or no animal-derived components. The production of highly attenuated live viruses can be better achieved when using specifically designed cell lines as producer substrate as opposed to using less defined primary cells. However, live viruses, thus produced comprise undesirable components from the cell lines and cell culture. The present invention relates to methods of production and purification of live enveloped viruses, which are suitable for vaccination.