The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2016

Filed:

Apr. 06, 2013
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Sungho Jin, San Diego, CA (US);

Seunghan Oh, Jeonbuk, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); C12M 1/00 (2006.01); A61K 9/00 (2006.01); A61L 27/06 (2006.01); A61L 27/30 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12M 23/34 (2013.01); A61K 9/0009 (2013.01); A61K 9/0024 (2013.01); A61K 9/0097 (2013.01); A61L 27/06 (2013.01); A61L 27/306 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); C12M 25/00 (2013.01); A61L 2300/254 (2013.01); A61L 2300/256 (2013.01); A61L 2300/406 (2013.01); A61L 2300/414 (2013.01); A61L 2300/416 (2013.01); A61L 2300/43 (2013.01); A61L 2300/624 (2013.01); A61L 2400/12 (2013.01);
Abstract

The invention provides articles of manufacture comprising biocompatible nanostructures comprising nanotubes and nanopores for, e.g., organ, tissue and/or cell growth, e.g., for bone, kidney or liver growth, and uses thereof, e.g., for in vitro testing, in vivo implants, including their use in making and using artificial organs, and related therapeutics. The invention provides lock-in nanostructures comprising a plurality of nanopores or nanotubes, wherein the nanopore or nanotube entrance has a smaller diameter or size than the rest (the interior) of the nanopore or nanotube. The invention also provides dual structured biomaterial comprising micro- or macro-pores and nanopores. The invention provides biomaterials having a surface comprising a plurality of enlarged diameter nanopores and/or nanotubes.


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