The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Nov. 21, 2011
Michael Shuler, Ithaca, NY (US);
Gregory T. Baxter, Salinas, CA (US);
Aaron Sin, Ithaca, NY (US);
Robert Andrew Harrison, Toronto, CA;
Scott Meyers, Norristown, PA (US);
Michael Shuler, Ithaca, NY (US);
Gregory T. Baxter, Salinas, CA (US);
Aaron Sin, Ithaca, NY (US);
Robert Andrew Harrison, Toronto, CA;
Scott Meyers, Norristown, PA (US);
Cornell Research Foundation, Inc., Ithaca, NY (US);
Abstract
A cell culture method using an in vitro microscale cell culture device having a first microscale chamber containing cells attached to an inner surface of the chamber and cell culture medium in contact with the cells. The cells are maintained in culture in the in vitro microscale cell culture device while flowing culture medium through the first chamber at a controlled rate to provide a liquid residence time value for the cells in the first chamber of the in vitro microscale cell culture device that is comparable to a liquid residence time value obtained with respect to comparable cells in vivo, such that metabolism by the cells in culture in the in vitro microscale cell culture device is comparable to metabolism by comparable cells in vivo.