The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Mar. 12, 2013
Applicant:
Glaxo Group Limited, Brentford, GB;
Inventors:
Paul Algate, Issaquah, WA (US);
Stephanie Jane Clegg, Stevenage, GB;
Jennifer L. Craigen, Stevenage, GB;
Paul Andrew Hamblin, Stevenage, GB;
Alan Peter Lewis, Stevenage, GB;
Patrick Mayes, Collegeville, PA (US);
Radha Shah Parmar, Stevenage, GB;
Trevor Anthony Kenneth Wattam, Stevenage, GB;
Assignee:
Glaxo Group Limited, Brentford, Middlesex, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3061 (2013.01); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/41 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.