The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
May. 10, 2013
Applicants:
Fujita Health University, Toyoake-shi, Aichi, JP;
Perseus Proteomics Inc., Tokyo, JP;
Inventors:
Assignees:
FUJITA HEALTH UNIVERSITY, Toyoake-shi, Aichi, JP;
Perseus Proteomics Inc., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C12N 15/13 (2006.01); C12N 15/85 (2006.01); G01N 33/68 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C07K 16/28 (2013.01); G01N 33/6893 (2013.01); C07K 2317/622 (2013.01);
Abstract
To provide a method for detecting cellular DNA damage by specifically recognizing molecules responsive to DNA strand breaks. A method for detecting DNA damage in cells, which comprises administering in vivo, to cells, an antibody against a cell membrane surface antigen that is expressed in cells undergoing DNA strand breaks to a greater extent than in cells not undergoing DNA strand breaks in an environment that causes DNA damage, and analyzing the expression status of the cell membrane surface antigen.