The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Nov. 02, 2012
Stefan Ewert, Allschwil, CH;
Adrian Auf Der Maur, Rutihof, CH;
Susann Cattepoel, Zurich, CH;
Roger Nitsch, Zumikon, CH;
Stefan Ewert, Allschwil, CH;
Adrian Auf Der Maur, Rutihof, CH;
Susann Cattepoel, Zurich, CH;
Roger Nitsch, Zumikon, CH;
Delenex Therapeutics AG, Schlieren, CH;
University of Zurich, Zürich, CH;
Abstract
The invention discloses an isolated antibody that selectively binds to the C-terminal part of Abeta and is humanized or fully human. The antibody of the invention is capable of preventing oligomerization of Abeta. Furthermore, a method of diagnosis comprising the steps of: (i) Labelling an antibody; (ii) Administering an effective dose of said antibody intranasally or systemically to a subject; and (iii) Detecting the concentration and/or presence of the labelled antibody in body parts of the subject is disclosed.