The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Aug. 30, 2013
Applicant:
Generon (Shanghai) Corporation Ltd., Shanghai, CN;
Inventors:
Xiaoqiang Yan, Shanghai, CN;
Zhihua Huang, Shanghai, CN;
Hongzhou Yang, Shanghai, CN;
Bill N. C. Sun, Shanghai, CN;
Yuliang Huang, Shanghai, CN;
Assignee:
Generon (Shanghai) Corporation Ltd., Shanghai, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 14/535 (2006.01); C12N 15/09 (2006.01); C12N 15/24 (2006.01); A61P 25/00 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
C07K 14/535 (2013.01); A61K 38/193 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural injury in animal, this invention can be used to protect neurons with the use of rhG-CSF dimer such that function of injured nerves can be restored. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased.