The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Dec. 19, 2013
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Edward John Belouski, Thousand Oaks, CA (US);
Murielle Marie Ellison, Thousand Oaks, CA (US);
Agnes Eva Hamburger, Newbury Park, CA (US);
Randy Ira Hecht, Raleigh, NC (US);
Yue-Sheng Li, Cambridge, MA (US);
Mark Leo Michaels, Encino, CA (US);
Jeonghoon Sun, San Diego, CA (US);
Jing Xu, Thousand Oaks, CA (US);
Assignee:
Amgen Inc., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/50 (2006.01); C12N 15/12 (2006.01); C12N 15/63 (2006.01); C07K 16/18 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/50 (2013.01); C07K 16/18 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The invention provides FGF21 mutant polypeptides with reduced proteolysis and aggregation, pharmaceutical compositions comprising the same.