The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Nov. 15, 2013
Applicants:
Novozymes A/s, Bagsvaerd, DK;
Novozymes, Inc., Davis, CA (US);
Inventors:
Mads Bjornvad, Virum, DK;
Debbie Yaver, Davis, CA (US);
Assignees:
NOVOZYMES, INC., Davis, CA (US);
NOVOZYMES A/S, Bagsvaerd, DK;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/00 (2006.01); C12N 9/20 (2006.01); C07K 14/37 (2006.01); C12N 15/62 (2006.01); C12N 15/81 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/37 (2013.01); C12N 9/20 (2013.01); C12N 15/625 (2013.01); C12N 15/81 (2013.01); C12P 21/02 (2013.01); C07K 2319/02 (2013.01);
Abstract
The present invention relates to methods for producing a polypeptide having biological activity, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first polynucleotide encoding the polypeptide operably linked to a second polynucleotide encoding a variant signal peptide or a variant prepropeptide; and (b) isolating the secreted polypeptide having biological activity from the cultivation medium.