The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2016

Filed:

Mar. 30, 2015
Applicant:

Abbvie Bahamas Limited, Nassau, BS;

Inventors:

Wouter I. Iwema Bakker, Weesp, NL;

Hein K. A. C. Coolen, Weesp, NL;

Axel Stoit, Weesp, NL;

Harmen Mons, Weesp, NL;

Eric Ronken, Weesp, NL;

Elizabeth Van Der Kam, Weesp, NL;

Jurjen Frankena, Weesp, NL;

Adrian Hobson, Worcester, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/15 (2006.01); C07D 265/30 (2006.01); C07D 265/32 (2006.01); C07D 279/12 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07F 9/6533 (2006.01);
U.S. Cl.
CPC ...
C07D 295/15 (2013.01); C07D 265/30 (2013.01); C07D 265/32 (2013.01); C07D 279/12 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07F 9/6533 (2013.01);
Abstract

The present disclosure relates to (thio)morpholine derivatives of the formula (I) or a pharmaceutically acceptable salt, a solvate or hydrate thereof; with the proviso that the derivative of formula (I) is not 2-(4-ethylphenyl)-4-morpholinoethanol or 4-[4-(2-hydroxyethyl)-2-morpholinyl]benzeneacetonitrile or a pharmaceutically acceptable salt, a solvate or hydrate thereof. The compounds of the invention have affinity to S1P receptors and may be used in the treatment, alleviation or prevention of S1P receptor mediated diseases and conditions.


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