IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9272990 B1

PDFFull Text
Date of Patent:
Mar. 01, 2016

Filed:

Dec. 06, 2011

Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis

Applicants:

Thomas Jon Seiders, San Diego, CA (US);

Bowei Wang, Westfield, NJ (US);

John Howard Hutchinson, San Diego, CA (US);

Nicholas Simon Stock, Encinitas, CA (US);

Deborah Volkots, New York, NY (US);

Inventors:

Thomas Jon Seiders, San Diego, CA (US);

Bowei Wang, Westfield, NJ (US);

John Howard Hutchinson, San Diego, CA (US);

Nicholas Simon Stock, Encinitas, CA (US);

Deborah Volkots, New York, NY (US);

Assignee:

AMIRA PHARMACEUTICALS, INC., Princeton, NJ (US);

Attorney:

Hoffmann & Baron, LLP

Primary Examiner:

Sreeni Padmanabhan

Assistant Examiner:

Sahar Javanmard

Int. Cl.
CPC ...
C07D 213/75 (2006.01); C07D 217/16 (2006.01); C07D 231/36 (2006.01); C07D 263/48 (2006.01); C07D 333/16 (2006.01); C07D 401/12 (2006.01); C07D 417/12 (2006.01); C07D 213/02 (2006.01); C07C 62/32 (2006.01); C07C 271/28 (2006.01); C07C 69/757 (2006.01); C07C 59/11 (2006.01); C07D 217/18 (2006.01); C07D 231/12 (2006.01); C07D 403/06 (2006.01);
U.S. Cl.
CPC ...
C07C 271/28 (2013.01); C07C 59/11 (2013.01); C07C 62/32 (2013.01); C07C 69/757 (2013.01); C07D 213/02 (2013.01); C07D 213/75 (2013.01); C07D 217/16 (2013.01); C07D 217/18 (2013.01); C07D 231/12 (2013.01); C07D 231/36 (2013.01); C07D 263/48 (2013.01); C07D 333/16 (2013.01); C07D 401/12 (2013.01); C07D 403/06 (2013.01); C07D 417/12 (2013.01); C07C 2101/02 (2013.01);
Abstract

Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.

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