The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Oct. 13, 2010
Applicants:
Wensheng Zhang, Sichuan, CN;
Jun Yang, Sichuan, CN;
Jin Liu, Sichuan, CN;
Inventors:
Assignee:
West China Hospital, Sichuan University, Sichuan, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 67/32 (2006.01); C07C 67/31 (2006.01); C07C 69/675 (2006.01); C07C 59/48 (2006.01);
U.S. Cl.
CPC ...
C07C 59/48 (2013.01); C07C 67/31 (2013.01); C07C 67/32 (2013.01); C07C 69/675 (2013.01);
Abstract
Hydroxy acid compound of substituted phenyl ester, preparation method and medical use thereof are provided. The title compound is shown in formula (I), Y═Cstraight carbon chain. The compound can release 2,6-diisopropylphenol rapidly under the action of enzymes in vivo, which has sedative, hypnotic and/or anesthetic effect. By protecting the hydroxyl group of 2, 6-diisopropylphenol in compound of formula (I), the first-pass metabolic activity of 2, 6-diisopropylphenol is reduced, so that the synthetic compound can be used for sedation, hypnosis, and/or anesthesia.