The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Apr. 29, 2009
Harald Rau, Heidelberg, DE;
Susanne Kinderman, Heidelberg, DE;
Torben Lebmann, Mannheim, DE;
Grethe Norskov Rasmussen, Farum, DK;
Ulrich Hersel, Heidelberg, DE;
Thomas Wegge, Heidelberg, DE;
Kennett Sprogoe, Palo Alto, CA (US);
Harald Rau, Heidelberg, DE;
Susanne Kinderman, Heidelberg, DE;
Torben Lebmann, Mannheim, DE;
Grethe Norskov Rasmussen, Farum, DK;
Ulrich Hersel, Heidelberg, DE;
Thomas Wegge, Heidelberg, DE;
Kennett Sprogoe, Palo Alto, CA (US);
Ascendis Pharma Growth Disorders Division A/S, Hellerup, DK;
Abstract
A chemically modified human Growth Hormone (rhGH) prepared by attaching a transient linker which comprises a polyethylene glycol. The chemically modified protein may have a much longer lasting rhGH activity than that of the unmodified rhGH, enabling reduced dose and scheduling opportunities and the modified rhGH may not cause lipoatrophy. Also includes methods of use for the treatment and/or prevention of diseases or disorders in which use of growth hormone is beneficial.