The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Mar. 14, 2013
Applicant:
University of Iowa Research Foundation, Iowa City, IA (US);
Inventors:
Paul B. McCray, Jr., Iowa City, IA (US);
Beverly L. Davidson, Iowa City, IA (US);
Sateesh Krishnamurthy, Iowa City, IA (US);
Assignee:
University of Iowa Research Foundation, Iowa City, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 38/18 (2006.01); A61K 31/713 (2006.01); A61K 31/7064 (2006.01); A61K 31/352 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61K 31/7105 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1808 (2013.01); A61K 31/352 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 31/7064 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01);
Abstract
The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.