The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 2016

Filed:

Mar. 25, 2014
Applicant:

Medprin Regenerative Medical Technologies Co., Ltd, Guangdong, CN;

Inventors:

Tao Xu, Guangdong, CN;

Yuyu Yuan, Guangdong, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 2/02 (2006.01); A61L 27/54 (2006.01); A61L 27/52 (2006.01); A61L 27/58 (2006.01); A61L 27/18 (2006.01); A61L 27/26 (2006.01); B32B 5/26 (2006.01); D04H 1/435 (2012.01); A61L 27/14 (2006.01); D01D 5/00 (2006.01); D04H 1/72 (2012.01); D04H 1/728 (2012.01); D04H 3/005 (2012.01); D04H 3/02 (2006.01); D04H 3/009 (2012.01); D04H 3/073 (2012.01); A61L 27/50 (2006.01); D04H 3/011 (2012.01);
U.S. Cl.
CPC ...
A61F 2/02 (2013.01); A61L 27/14 (2013.01); A61L 27/18 (2013.01); A61L 27/26 (2013.01); A61L 27/50 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); B32B 5/26 (2013.01); D01D 5/003 (2013.01); D04H 1/435 (2013.01); D04H 1/72 (2013.01); D04H 1/728 (2013.01); D04H 3/005 (2013.01); D04H 3/009 (2013.01); D04H 3/011 (2013.01); D04H 3/02 (2013.01); D04H 3/073 (2013.01); B32B 2250/20 (2013.01); B32B 2307/7163 (2013.01); B32B 2307/728 (2013.01); B32B 2307/73 (2013.01); B32B 2535/00 (2013.01);
Abstract

Disclosed are an artificial dura mater and manufacturing method thereof. The artificial dura mater includes electrospun layers prepared by electrostatic spinning, at least one of which is a hydrophobic electrospun layer. Further, above the hydrophobic electrospun layer, there can be at least one hydrophilic electrospun layer. A transition layer can be further included between the hydrophobic and the hydrophilic electrospun layers. Additionally, cytokines and/or medicines can be affixed to either or both of the hydrophobic and the hydrophilic electrospun layers, by way of bio-printing. The disclosed artificial dura mater shows good biocompatibility, enhances dural tissue regeneration, achieves excellent repairing effects, prevents adhesion, allows complete absorption, has good mechanical properties, ensures low infection rates, and can be loaded with therapeutic agents.


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