The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 2016
Filed:
Jun. 19, 2013
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Inventors:
Lynette Cegelski, Stanford, CA (US);
Ji Youn Lim, Stanford, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 35/00 (2006.01); A61K 31/12 (2006.01); A01N 35/02 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A01N 35/02 (2013.01); A61K 31/12 (2013.01); A61K 45/06 (2013.01);
Abstract
Compositions and methods for the dissolution of a microbial biofilm are provided, where the method comprises contacting a microbiofilm with an effective dose of a curcumin derivative as a biofilm inhibitor. In some embodiments the curcumin derivative is dimethoxycurcumin. In some embodiments the biofilm comprises, e.g. including uropathogenic. The biofilm can be present in vitro or in vivo. The biofilm inhibitor may be administered alone, or in combination with bacteriocidal agents.