The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

Apr. 30, 2014
Applicant:

Customarray, Inc., Bothell, WA (US);

Inventors:

Karl Maurer, Everett, WA (US);

John J Cooper, Seattle, WA (US);

Assignee:

CustomArray, Inc., Bothwell, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07B 41/02 (2006.01); C07B 41/06 (2006.01); C25B 3/10 (2006.01);
U.S. Cl.
CPC ...
C25B 3/10 (2013.01); C07B 41/02 (2013.01); C07B 41/06 (2013.01); C07H 21/02 (2013.01); C07H 21/04 (2013.01);
Abstract

There is disclosed an electrochemical deblocking solution for use on an electrode microarray. There is further disclosed a method for electrochemical synthesis on an electrode array using the electrochemical deblocking solution. The solution and method are for removing acid-labile protecting groups for synthesis of oligonucleotides, peptides, small molecules, or polymers on a microarray of electrodes while substantially improving isolation of deblocking to active electrodes. The method comprises applying a voltage or a current to at least one electrode of an array of electrodes. The array of electrodes is covered by the electrochemical deblocking solution.


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