The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
Aug. 23, 2007
Applicants:
David J. Lockhart, Del Mar, CA (US);
Patrick Parvis Zarrinkar, San Diego, CA (US);
Daniel Kelly Treiber, San Diego, CA (US);
Inventors:
David J. Lockhart, Del Mar, CA (US);
Patrick Parvis Zarrinkar, San Diego, CA (US);
Daniel Kelly Treiber, San Diego, CA (US);
Assignee:
DiscoveRx Corporation, Fremont, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/48 (2006.01); G01N 33/566 (2006.01); G01N 33/543 (2006.01); G01N 33/577 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/485 (2013.01); G01N 33/543 (2013.01); G01N 33/566 (2013.01); G01N 33/577 (2013.01); G01N 2333/912 (2013.01); G01N 2500/02 (2013.01);
Abstract
The invention provides methods for determining the interactions between phage-displayed proteins and test molecules. The phage-displayed proteins are contacted with a reference moiety in the presence and absence of a test molecule; the behavior of the phage-displayed proteins as a function of concentration of the test molecule permits calculation of the binding affinity of the phage-displayed protein for the test molecule.