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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9267142 B1

PDFFull Text
Expired
Date of Patent:
Feb. 23, 2016

Filed:

Jan. 25, 2011

Recombinant protein production in heterologous systems

Applicants:

Yitzhak Pilpel, Rehovot, IL;

Tamir Tuller, Rehovot, IL;

Sivan Navon, Rehovot, IL;

Menachem Rubinstein, Tel-Aviv, IL;

Inventors:

Yitzhak Pilpel, Rehovot, IL;

Tamir Tuller, Rehovot, IL;

Sivan Navon, Rehovot, IL;

Menachem Rubinstein, Tel-Aviv, IL;

Assignee:

Yeda Research and Development Co. Ltd., Rehovot, IL;

Attorney:
Primary Examiner:

Michele K Joike

Int. Cl.
CPC ...
C07H 21/02 (2006.01); C12N 15/67 (2006.01); C07K 14/505 (2006.01); C07K 14/555 (2006.01); C07K 14/59 (2006.01); C07K 14/61 (2006.01); C07K 14/62 (2006.01); C07K 14/705 (2006.01); C07K 14/755 (2006.01); C12N 9/40 (2006.01); C12P 21/02 (2006.01); C12N 9/24 (2006.01);
U.S. Cl.
CPC ...
C12N 15/67 (2013.01); C07K 14/505 (2013.01); C07K 14/555 (2013.01); C07K 14/59 (2013.01); C07K 14/61 (2013.01); C07K 14/62 (2013.01); C07K 14/705 (2013.01); C07K 14/755 (2013.01); C12N 9/2402 (2013.01); C12N 9/2465 (2013.01); C12P 21/02 (2013.01);
Abstract

Isolated polynucleotides are disclosed which increase the efficiency of gene expression in a heterologous cell. The polynucleotide sequences which encode polypeptides are adapted such that the average rate of translation of the first at least about 30 amino acids is slower by at least two fold than the average rate of translation of the remaining amino acids of the polypeptide.

Find Patent Forward Citations

Pilpel, Yitzhak. (2016). Recombinant protein production in heterologous systems (U.S. Patent No. 9267142). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9267142

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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